BioMicroCenter: Difference between revisions

From BioMicro Center

Latest revision as of 19:00, 24 April 2026

Welcome to the MIT BioMicro Center!

The MIT BioMicro Center is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the Department of Biology, the Koch Institute for Integrative Cancer Research (Integrated Genomics and Bioinformatics Core (IGB)), and the Department of Biological Engineering.

Assisted Services

Walkup Services

Sample Isolation

Sonication (Covaris E220/R230)
DNA/RNA purification (Chemagic360)
Quality Control
(AATI Fragment Analyzer/FemtoPulse)

Library Preparation

Short Read Sample Preparation
- High Throughput Methods for *DNA* *RNA*
Long Read Sample Preparation
(Nanopore and PacBio)

Walk-up Instrumentation

Includes: qPCR (LC480), Plate Readers (Varioskan/Synergy H1)
BioAnalyzer, NanoDrop, Covaris, Pippin Prep
Tecan/Chemagic automation
MiSeq i100, 10x Chromium X

Single Cell and Spatial

10X CHROMIUM
(5'RNA, 3'RNA, ATAC, multiome)
10X VISIUM
(Standard, High Density)
ELEMENT AVITI24 (in situ prep/sequencing)

Sequencing Technologies

Short Read
- High Yield (>1b reads): Illumina NovaSeqX (25b,10b)†
- Mid Yield (250m-1b reads): Element AVITI24
- Low Yield (1m-150m reads): SingularG4, Illumina MiSeq i100
Long Read (1kb+)
- PacBio Revio†

Automation / Library Prep

Informatics Services

Data Analysis

BioIT/Research Computing

Education/Training/Seminars

† - service will be performed in a sister core facility (Harvard, DFCI, or Broad)

BMC Internal wiki

CONTACT US

68-322
biomicro@mit.edu
617-715-4533

Retrieved from "http://bmcwiki.mit.edu/index.php?title=BioMicroCenter&oldid=131404"

@@ Line 7: / Line 7: @@
   | valign="top" align="left"|
 * [[BioMicroCenter:News|'''News & General Information''']]
-* [[BioMicroCenter:Pricing|Pricing]]
+* [[BioMicroCenter:Pricing|Pricing]] / [[MIT:Pricing|MIT Pricing]]
-* Internal Sample Submission for <BR>[https://mit-ki.ilabsolutions.com/sc/3381/ki-genomics-core-mit-biomicro-center?tab=about Genomics] and [https://mit-ki.ilabsolutions.com/sc/3189/bioinformatics-and-computing-core/?tab=services Informatics] (ilabs)
+* [[BioMicroCenter:Submission|Sample Submission]]
+* [[BioMicroCenter:Consumables|Consumables]]
+* [[BioMicroCenter:Consulting|Experimental Design]]
   | valign="top" align="left"|
+* [[BioMicroCenter:AboutBMC|About the BioMicro Center]]
 * [[BioMicroCenter:People| Staff]]
+* [[BioMicroCenter:Consulting| Getting Started]]
 <!-- [[BioMicroCenter:Jobs|Positions Available]] -->
-* [[BioMicroCenter:Forms#NEW_USERS|New User Signup Forms]]
-* [[BioMicroCenter:Forms|External Submission Forms]]
 * [[BioMicroCenter:FAQ|FAQs]]
 |}
@@ Line 22: / Line 24: @@
   |colspan=2 align="center" style="background-color:yellow; border:1px solid purple"|
   {|
-   |<BIG><B>Assisted Services </B></BIG>
+   |<BIG><B>[[BioMicroCenter:Assisted_Services|Assisted Services]] </B></BIG>
   |}
   |align="center" style="background-color:aqua; border:1px solid black"|
@@ Line 45: / Line 47: @@
 * Long Read Sample Preparation<BR>([[BioMicroCenter:NanoPore_Library_Prep|Nanopore]] and [[BioMicroCenter:PacBio_Library_Preparation|PacBio]])
   |}
- |valign="top" align="center" style="background-color:transparent; border:1px solid black"|
+|valign="top" align="center" style="background-color:transparent; border:1px solid black"|
   {|
-   |width="10%" align="left"|<BIG><B>Sample Quantification</B></BIG>
+   |width="10%" align="left"|<BIG><B>[[BioMicroCenter:Walkup Services|Walk-up Instrumentation]]</B></BIG>
-* Plate Readers ([[BioMicroCenter:Varioskan#Synergy_H1| Synergy H1]]/[[BioMicroCenter:Varioskan| Varioskan]])
+<small>Includes: qPCR (LC480), Plate Readers (Varioskan/Synergy H1)<BR> BioAnalyzer, NanoDrop, Covaris, Pippin Prep<BR> Tecan/Chemagic automation<BR> MiSeq i100, 10x Chromium X</small>
-* [[BioMicroCenter:RTPCR|RT-PCR (Roche LC480)]]
-* [[BioMicroCenter:QC| BioAnalyzer2100]]
-* [[BioMicroCenter:QC#NanoDrop_ND-1000| NanoDrop ND-1000]]
   |}
@@ Line 58: / Line 57: @@
   {|
    |width="10%" align="left"|<BIG><B>
-[[BioMicroCenter:SingleCell|Single Cell]] and Spatial</B></BIG>
+[[BioMicroCenter:SingleCell|Single Cell]] and [[BioMicroCenter:SpTx|Spatial]]</B></BIG>
 * 10X CHROMIUM <BR> <small> (5'RNA, 3'RNA, ATAC, multiome) </small>
 * 10X VISIUM <BR> <small> (Standard, High Density) </small>
@@ Line 66: / Line 65: @@
   {|
    |width="10%" align="left"|<BIG><B> [[BioMicroCenter:Sequencing|Sequencing Technologies]] </B></BIG>
-* High Yield (>1b reads) <small>
+* [[BioMicroCenter:ShortRead|Short Read]]
-**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeqX (25b,10b)]]†</small>
+** High Yield (>1b reads): Illumina NovaSeqX (25b,10b)†
-* Mid Yield (250m-1b reads) <small>
+** Mid Yield (250m-1b reads): Element AVITI24
-**[[BioMicroCenter:Element Sequencing|Element AVITI24]] </small>
+** Low Yield (1m-150m reads): SingularG4, Illumina MiSeq i100
-* Low Yield (1m-150m reads) <small>
-**[[BioMicroCenter:Singular Sequencing|SingularG4]]
-**[[BioMicroCenter:Illumina_Sequencing|Illumina MiSeq i100]]</small>
 * Long Read (1kb+) <small>
 **[[BioMicroCenter:Oxford Nanopore Technologies|ONT PromethION]]
@@ Line 94: / Line 90: @@
   |valign="top" align="center" style="background-color:transparent; border:1px solid black"|
   {|
-   |width="10%" align="left"|<BIG><B>Data Analysis</B></BIG>
+   |width="10%" align="left"|<BIG><B>[[BioMicroCenter:Analysis|Data Analysis]]</B></BIG>
 * [https://igb.mit.edu/ Bioinformatic Consulting]
 * [[BioMicroCenter:People#INFORMATICS_LAB|Informatics Staff]]