BioMicroCenter

Welcome to the MIT BioMicro Center!

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The MIT BioMicro Center is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the Department of Biology, the Koch Institute for Integrative Cancer Research (Integrated Genomics and Bioinformatics Core (IGB)), and the Department of Biological Engineering.

Assisted Services		Walkup Services
Sample Isolation Sonication (Covaris E220/R230) DNA/RNA purification (Chemagic360) Quality Control (AATI Fragment Analyzer/FemtoPulse)	Library Preparation Short Read Sample Preparation Standard Methods for *DNA* *RNA* High Throughput Methods for *DNA* *RNA* Long Read Sample Preparation (Nanopore and PacBio)	Sample Quantification Plate Readers ( Synergy H1/ Varioskan) RT-PCR (Roche LC480) BioAnalyzer2100 NanoDrop ND-1000
Single Cell and Spatial 10X CHROMIUM (5'RNA, 3'RNA, ATAC, multiome, flex) 10X VISIUM (Std & HD) ELEMENT AVITI24 (in situ prep/sequencing)	Sequencing Technologies High Yield (>1b reads) Illumina NovaSeqX (25b,10b)† Illumina NovaSeq6000 (S2,S4) Mid Yield (250m-1b reads) Element AVITI24 Illumina NovaSeq6000 Illumina NextSeq500 Low Yield (1m-150m reads) SingularG4 Illumina MiSeq Long Read (1kb+) ONT PromethION PacBio Revio†	Automation / Library Prep Liquid Handlers (Tecan EVO SPT Mosquito) Covaris E220 and R230 Focused-ultrasonicators Pippin Prep automated electrophoresis system Oligo Synthesis
Data Analysis Bioinformatic Consulting	Data Management/BioIT Data Management Servers Software	Education/Training/Seminars Informatics Training Sessions Technology Seminar Series Biostuff mailing list

† - service will be performed in a sister core facility (Harvard, DFCI, or Broad)

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CONTACT US

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biomicro@mit.edu
617-715-4533