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* Internal Sample Submission for <BR>[https://mit-ki.ilabsolutions.com/sc/3381/ki-genomics-core-mit-biomicro-center?tab=about Genomics] and [https://mit-ki.ilabsolutions.com/sc/3189/bioinformatics-and-computing-core/?tab=services Informatics] (ilabs)
* Internal Sample Submission for <BR>[https://mit-ki.ilabsolutions.com/sc/3381/ki-genomics-core-mit-biomicro-center?tab=about Genomics] and [https://mit-ki.ilabsolutions.com/sc/3189/bioinformatics-and-computing-core/?tab=services Informatics] (ilabs)
  | valign="top" align="left"|
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* [[BioMicroCenter:People| Staff]] <!--/ [[BioMicroCenter:Jobs|Positions Available]]-->
* [[BioMicroCenter:People| Staff]]  
<!-- [[BioMicroCenter:Jobs|Positions Available]] -->
* [[BioMicroCenter:Forms#NEW_USERS|New User Signup Forms]]
* [[BioMicroCenter:Forms#NEW_USERS|New User Signup Forms]]
* [[BioMicroCenter:Forms|External Submission Forms]]
* [[BioMicroCenter:Forms|External Submission Forms]]
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   |width="10%" align="left"|<BIG><B>Sample Isolation</B></BIG>
   |width="10%" align="left"|<BIG><B>Sample Isolation</B></BIG>
* Sonication ([[BioMicroCenter:Covaris|Covaris E220/R230]])
* Sonication ([[BioMicroCenter:Covaris|Covaris E220/R230]])
* DNA/RNA purification ([[BioMicroCenter:Tecan_Freedom_Evo#verrity_Chemagic_360|Chemagic360]])
* DNA/RNA purification ([[BioMicroCenter:Tecan_Freedom_Evo#Revvity_Chemagic_360|Chemagic360]])
* Quality Control<BR>([[BioMicroCenter:QC|AATI Fragment Analyzer/FemtoPulse]])
* Quality Control<BR>([[BioMicroCenter:QC|AATI Fragment Analyzer/FemtoPulse]])
  |}
  |}
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** Standard Methods for [[BioMicroCenter:DNA_LIB| *DNA* ]] [[BioMicroCenter:RNA_LIB| *RNA* ]]
** Standard Methods for [[BioMicroCenter:DNA_LIB| *DNA* ]] [[BioMicroCenter:RNA_LIB| *RNA* ]]
** [[BioMicroCenter:FAQ#STANDARD_versus_HIGH_THROUGHPUT_LIBRARY_PREPARATION|High Throughput Methods]] for [[BioMicroCenter:DNA_HTL| *DNA* ]]  [[BioMicroCenter:RNA_HTL| *RNA* ]]</small>
** [[BioMicroCenter:FAQ#STANDARD_versus_HIGH_THROUGHPUT_LIBRARY_PREPARATION|High Throughput Methods]] for [[BioMicroCenter:DNA_HTL| *DNA* ]]  [[BioMicroCenter:RNA_HTL| *RNA* ]]</small>
* Long Read Sample Preparation<BR>(Nanopore and PacBio)
* Long Read Sample Preparation<BR>([[BioMicroCenter:NanoPore_Library_Prep|Nanopore]] and [[BioMicroCenter:PacBio_Library_Preparation|PacBio]])
  |}
  |}
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   |width="10%" align="left"|<BIG><B>Sample Quantification</B></BIG>
   |width="10%" align="left"|<BIG><B>Sample Quantification</B></BIG>
* Plate Readers ([[BioMicroCenter:Varioskan#Synergy_H1| Synergy H1]]/[[BioMicroCenter:Varioskan| Varioskan]])
* Plate Readers ([[BioMicroCenter:Varioskan#Synergy_H1| Synergy H1]]/[[BioMicroCenter:Varioskan| Varioskan]])
* [[BioMicroCenter:RTPCR| PCR and RT-PCR]]
* [[BioMicroCenter:RTPCR|RT-PCR (Roche LC480)]]
* [[BioMicroCenter:QC| BioAnalyzer2100]]
* [[BioMicroCenter:QC| BioAnalyzer2100]]
* [[BioMicroCenter:QC#NanoDrop_ND-1000| NanoDrop ND-1000]]
* [[BioMicroCenter:QC#NanoDrop_ND-1000| NanoDrop ND-1000]]
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  {|
  {|
   |width="10%" align="left"|<BIG><B>Single Cell and Spatial</B></BIG>
   |width="10%" align="left"|<BIG><B>  
* [[BioMicroCenter:SingleCell|10X CHROMIUM]] <BR> (5'RNA, 3'RNA, ATAC, multiome, flex)
[[BioMicroCenter:SingleCell|Single Cell]] and [[BioMicroCenter:SpTx|Spatial]]</B></BIG>
* 10X VISIUM (Std & HD)
* 10X CHROMIUM <BR> <small> (5'RNA, 3'RNA, ATAC, multiome) </small>
* 10X VISIUM <BR> <small> (Standard, High Density) </small>
* ELEMENT AVITI24 (<i>in situ</i> prep/sequencing)
* ELEMENT AVITI24 (<i>in situ</i> prep/sequencing)
  |}
  |}
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   |width="10%" align="left"|<BIG><B> [[BioMicroCenter:Sequencing|Sequencing Technologies]] </B></BIG>
   |width="10%" align="left"|<BIG><B> [[BioMicroCenter:Sequencing|Sequencing Technologies]] </B></BIG>
* High Yield (>1b reads) <small>
* High Yield (>1b reads) <small>
**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeqX (25b,10b)]]†
**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeqX (25b,10b)]]†</small>
**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeq6000 (S2,S4)]]</small>
* Mid Yield (250m-1b reads) <small>
* Mid Yield (250m-1b reads) <small>
**[[BioMicroCenter:Element Sequencing|Element AVITI24]]
**[[BioMicroCenter:Element Sequencing|Element AVITI24]] </small>
**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeq6000]]
**[[BioMicroCenter:Illumina_Sequencing|Illumina NextSeq500]]</small>
* Low Yield (1m-150m reads) <small>
* Low Yield (1m-150m reads) <small>
**[[BioMicroCenter:Singular Sequencing|SingularG4]]
**[[BioMicroCenter:Singular Sequencing|SingularG4]]
**[[BioMicroCenter:Illumina_Sequencing|Illumina MiSeq]]</small>
**[[BioMicroCenter:Illumina_Sequencing|Illumina MiSeq i100]]</small>
* Long Read (1kb+) <small>
* Long Read (1kb+) <small>
**[[BioMicroCenter:Oxford Nanopore Technologies|ONT PromethION]]  
**[[BioMicroCenter:Oxford Nanopore Technologies|ONT PromethION]]  
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* [[BioMicroCenter:Oligo_Synthesis| Oligo Synthesis]]
* [[BioMicroCenter:Oligo_Synthesis| Oligo Synthesis]]
  |}
  |}
 
|-
|valign="top" colspan=3 align="center" style="background-color: lightsalmon; border:1px solid black"|
{|
  |<BIG><B>Informatics Services</B></BIG>
|}
  |-
  |-
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  {|
  {|
   |width="10%" align="left"|[[BioMicroCenter:Computing|<BIG><B>Data Analysis</B></BIG>]]
   |width="10%" align="left"|<BIG><B>Data Analysis</B></BIG>
* [[BioMicroCenter:BioInformaticsStaff|Bioinformatic Consulting]]
* [https://igb.mit.edu/ Bioinformatic Consulting]
* [[BioMicroCenter:People#INFORMATICS_LAB|Informatics Staff]]
  |}
  |}
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  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |width="10%" align="left"|<BIG><B>Data Management/BioIT</B></BIG>
   |width="10%" align="left"|<BIG><B>BioIT/Research Computing</B></BIG>
* [https://koch-institute-mit.gitbook.io/mit-data-management-analysis-core/ Data Management]
* [https://koch-institute-mit.gitbook.io/mit-data-management-analysis-core/ FAIR Data Management]
* [[BioMicroCenter:Computing#HARDWARE|Servers]]
* [https://igb.mit.edu/computing-resources/active-data-storage Data Storage]
* [[BioMicroCenter:Computing#SOFTWARE|Software]]
* [https://igb.mit.edu/computing-resources/luria-cluster Computing on Luria]
* [https://igb.mit.edu/data-management/globus Data Transfer (Globus)]
  |}
  |}
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  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |width="10%" align="left"|<BIG><B>Education/Training/Seminars</B></BIG>
   |width="10%" align="left"|<BIG><B>Education/Training/Seminars</B></BIG>
* [[BioMicroCenter:BioinfoClasses|Informatics Training Sessions]]
* [https://igb.mit.edu/mini-courses Informatics/Computing Training Sessions]
* [[BioMicroCenter:Technology_Seminar_Series|Technology Seminar Series]]
* [[BioMicroCenter:Technology_Seminar_Series|Technology Seminar Series]]
* [http://mailman.mit.edu:/mailman/listinfo/biostuff Biostuff mailing list]
* [http://mailman.mit.edu:/mailman/listinfo/biostuff Biostuff mailing list]

Latest revision as of 12:42, 25 August 2025

Welcome to the MIT BioMicro Center!

The MIT BioMicro Center is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the Department of Biology, the Koch Institute for Integrative Cancer Research (Integrated Genomics and Bioinformatics Core (IGB)), and the Department of Biological Engineering.

Assisted Services
Walkup Services
Sample Isolation
Library Preparation
Sample Quantification

Single Cell and Spatial

  • 10X CHROMIUM
    (5'RNA, 3'RNA, ATAC, multiome)
  • 10X VISIUM
    (Standard, High Density)
  • ELEMENT AVITI24 (in situ prep/sequencing)
Sequencing Technologies
Automation / Library Prep
Informatics Services
Data Analysis
BioIT/Research Computing
Education/Training/Seminars

† - service will be performed in a sister core facility (Harvard, DFCI, or Broad)


BMC Internal wiki

CONTACT US

68-322
biomicro@mit.edu
617-715-4533

Retrieved from "http://bmcwiki.mit.edu/index.php?title=BioMicroCenter&oldid=106864"