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NOTE: This is an archival version of the wiki and may not be up to date. We are working to address this issue.
<h2 align="center"> Welcome to the MIT BioMicro Center! </h2>
<h2 align="center"> Welcome to the MIT BioMicro Center! </h2>


The '''MIT BioMicro Center''' is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the [http://biology.mit.edu Department of Biology], the [http://ki.mit.edu Koch Institute for Integrative Cancer Research] (Integrated Genomics and Bioinformatics Core (IGB)), and the [http://web.mit.edu/be Department of Biological Engineering].
<BR><BR>
{| width="100%"  
{| width="100%"  
  |- valign="top"
  |-  
|[[File:logo.png|left]]
|valign="top"|
  | valign="top" align="left" height="145px"|
[[File:logo.png|left]]
<BIG><B> The BioMicro Center </B></BIG>
  | valign="top" align="left"|
* [[BioMicroCenter:News|'''News & General Information''']]
* [[BioMicroCenter:News|'''News & General Information''']]
* [[BioMicroCenter:People| Staff]] <!--/ [[BioMicroCenter:Jobs|Positions Available]]-->
* [[BioMicroCenter:Forms|User signup forms and Sample Submission Forms for external users]]
* [[BioMicroCenter:Pricing|Pricing]]
* [[BioMicroCenter:Pricing|Pricing]]
* Internal Sample Submission for <BR>[https://mit-ki.ilabsolutions.com/sc/3381/ki-genomics-core-mit-biomicro-center?tab=about Genomics] and [https://mit-ki.ilabsolutions.com/sc/3189/bioinformatics-and-computing-core/?tab=services Informatics] (ilabs)
| valign="top" align="left"|
* [[BioMicroCenter:People| Staff]]
<!-- [[BioMicroCenter:Jobs|Positions Available]] -->
* [[BioMicroCenter:Forms#NEW_USERS|New User Signup Forms]]
* [[BioMicroCenter:Forms|External Submission Forms]]
* [[BioMicroCenter:FAQ|FAQs]]
* [[BioMicroCenter:FAQ|FAQs]]
|}
|}
The '''MIT BioMicro Center''' is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the [http://biology.mit.edu Department of Biology], the [http://ki.mit.edu Koch Institute for Integrative Cancer Research] (Integrated Genomics and Bioinformatics Core (IGB)), and the [http://web.mit.edu/be Department of Biological Engineering].


{| width="100%"
{| width="100%"
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   |<BIG><B> Walkup Services </B></BIG>
   |<BIG><B> Walkup Services </B></BIG>
  |}
  |}
  |-
  |-
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Sample Isolation</B></BIG>
   |width="10%" align="left"|<BIG><B>Sample Isolation</B></BIG>
* DNA/RNA purification ([[BioMicroCenter:Tecan_Freedom_Evo#verrity_Chemagic_360|Chemagic360]])
* Sonication ([[BioMicroCenter:Covaris|Covaris E220/R230]])
* DNA/RNA purification ([[BioMicroCenter:Tecan_Freedom_Evo#Revvity_Chemagic_360|Chemagic360]])
* Quality Control<BR>([[BioMicroCenter:QC|AATI Fragment Analyzer/FemtoPulse]])
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Library Preparation</B></BIG>
   |width="10%" align="left"|<BIG><B>Library Preparation</B></BIG>
* [[BioMicroCenter:Illumina_Library_Preparation|Short Read Sample Preparation]]
* [[BioMicroCenter:Illumina_Library_Preparation|Short Read Sample Preparation]]<small>
** Standard Methods for [[BioMicroCenter:DNA_LIB| *DNA* ]] [[BioMicroCenter:RNA_LIB| *RNA* ]]
** Standard Methods for [[BioMicroCenter:DNA_LIB| *DNA* ]] [[BioMicroCenter:RNA_LIB| *RNA* ]]
** High Throughput Methods for [[BioMicroCenter:DNA_HTL| *DNA* ]]  [[BioMicroCenter:RNA_HTL| *RNA* ]]
** [[BioMicroCenter:FAQ#STANDARD_versus_HIGH_THROUGHPUT_LIBRARY_PREPARATION|High Throughput Methods]] for [[BioMicroCenter:DNA_HTL| *DNA* ]]  [[BioMicroCenter:RNA_HTL| *RNA* ]]</small>
 
* Long Read Sample Preparation<BR>([[BioMicroCenter:NanoPore_Library_Prep|Nanopore]] and [[BioMicroCenter:PacBio_Library_Preparation|PacBio]])
 
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Sample Quantification</B></BIG>
   |width="10%" align="left"|<BIG><B>Sample Quantification</B></BIG>
* Plate Readers ([[BioMicroCenter:Varioskan#Synergy_H1| Synergy H1]]/[[BioMicroCenter:Varioskan| Varioskan]])
* Plate Readers ([[BioMicroCenter:Varioskan#Synergy_H1| Synergy H1]]/[[BioMicroCenter:Varioskan| Varioskan]])
* [[BioMicroCenter:RTPCR| PCR and RT-PCR]]
* [[BioMicroCenter:RTPCR|RT-PCR (Roche LC480)]]
* [[BioMicroCenter:QC|BioAnalyzer / AATI Fragment Analyzer / Femto Pulse]]
* [[BioMicroCenter:QC| BioAnalyzer2100]]
* [[BioMicroCenter:QC#NanoDrop_ND-1000| NanoDrop ND-1000]]
  |}
  |}
  |-
  |-
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Single Cell and Spatial</B></BIG>
   |width="10%" align="left"|<BIG><B>  
* [[BioMicroCenter:SingleCell|Single Cell Prep, Sequencing and Analysis]]
[[BioMicroCenter:SingleCell|Single Cell]] and [[BioMicroCenter:SpTx|Spatial]]</B></BIG>
* 10X CHROMIUM <BR> <small> (5'RNA, 3'RNA, ATAC, multiome) </small>
* 10X VISIUM <BR> <small> (Standard, High Density) </small>
* ELEMENT AVITI24 (<i>in situ</i> prep/sequencing)
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B> [[BioMicroCenter:Sequencing|Sequencing Technologies]] </B></BIG>
   |width="10%" align="left"|<BIG><B> [[BioMicroCenter:Sequencing|Sequencing Technologies]] </B></BIG>
* [[BioMicroCenter:Illumina_Sequencing|Illumina Sequencing]] (NovaSeq, NextSeq, MiSeq)
* High Yield (>1b reads) <small>
* [[BioMicroCenter:Singular Sequencing|Singular Sequencing]] (G4)
**[[BioMicroCenter:Illumina_Sequencing|Illumina NovaSeqX (25b,10b)]]†</small>
* [[BioMicroCenter:Element Sequencing|Element Sequencing]] (AVITI24)
* Mid Yield (250m-1b reads) <small>
* [[BioMicroCenter:PacBio| PacBio Sequencing]] with Revio
**[[BioMicroCenter:Element Sequencing|Element AVITI24]] </small>
* [[BioMicroCenter:Oxford Nanopore Technologies| Nanopore Sequencing]] with PromethION
* Low Yield (1m-150m reads) <small>
**[[BioMicroCenter:Singular Sequencing|SingularG4]]
**[[BioMicroCenter:Illumina_Sequencing|Illumina MiSeq i100]]</small>
* Long Read (1kb+) <small>
**[[BioMicroCenter:Oxford Nanopore Technologies|ONT PromethION]]
**[[BioMicroCenter:PacBio|PacBio Revio]]†</small>
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Automation / Library Prep</B></BIG>
   |width="10%" align="left"|<BIG><B>Automation / Library Prep</B></BIG>
* [[BioMicroCenter:Tecan Freedom Evo|Liquid Handlers]] ([[BioMicroCenter:Tecan_Freedom_Evo#JOHNNY_5|Tecan EVO]]
* [[BioMicroCenter:Tecan Freedom Evo|Liquid Handlers]] ([[BioMicroCenter:Tecan_Freedom_Evo#JOHNNY_5|Tecan EVO]]
* [[BioMicroCenter:Tecan_Freedom_Evo#SPT_LABTECH_MOSQUITO_HV|SPT Mosquito]])
* [[BioMicroCenter:Tecan_Freedom_Evo#SPT_LABTECH_MOSQUITO_HV|SPT Mosquito]])
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* [[BioMicroCenter:PippinPrep|Pippin Prep automated electrophoresis system]]
* [[BioMicroCenter:PippinPrep|Pippin Prep automated electrophoresis system]]
* [[BioMicroCenter:Oligo_Synthesis| Oligo Synthesis]]
* [[BioMicroCenter:Oligo_Synthesis| Oligo Synthesis]]
|}
|-
|valign="top" colspan=3 align="center" style="background-color: lightsalmon; border:1px solid black"|
{|
  |<BIG><B>Informatics Services</B></BIG>
  |}
  |}
  |-
  |-
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|[[BioMicroCenter:Computing|<BIG><B>Data Analysis</B></BIG>]]
   |width="10%" align="left"|<BIG><B>Data Analysis</B></BIG>
* [[BioMicroCenter:BioInformaticsStaff|Bioinformatic Consulting]]
* [https://igb.mit.edu/ Bioinformatic Consulting]
* [[BioMicroCenter:People#INFORMATICS_LAB|Informatics Staff]]
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Data Management/BioIT</B></BIG>
   |width="10%" align="left"|<BIG><B>BioIT/Research Computing</B></BIG>
* [https://koch-institute-mit.gitbook.io/mit-data-management-analysis-core/ Data Management]
* [https://koch-institute-mit.gitbook.io/mit-data-management-analysis-core/ FAIR Data Management]
* [[BioMicroCenter:Computing#HARDWARE|Servers]]
* [https://igb.mit.edu/computing-resources/active-data-storage Data Storage]
* [[BioMicroCenter:Computing#SOFTWARE|Software]]
* [https://igb.mit.edu/computing-resources/luria-cluster Computing on Luria]
* [https://igb.mit.edu/data-management/globus Data Transfer (Globus)]
  |}
  |}
  |align="center" style="background-color:transparent; border:1px solid black"|  
  |valign="top" align="center" style="background-color:transparent; border:1px solid black"|  
  {|
  {|
   |valign="top" width="10%" align="left"|<BIG><B>Education/Training/Seminars</B></BIG>
   |width="10%" align="left"|<BIG><B>Education/Training/Seminars</B></BIG>
* [[BioMicroCenter:BioinfoClasses|Informatics Training Sessions]]
* [https://igb.mit.edu/mini-courses Informatics/Computing Training Sessions]
* [[BioMicroCenter:Technology_Seminar_Series| Technology Seminar Series]]
* [[BioMicroCenter:Technology_Seminar_Series|Technology Seminar Series]]
* [http://mailman.mit.edu:/mailman/listinfo/biostuff Biostuff mailing list]
* [http://mailman.mit.edu:/mailman/listinfo/biostuff Biostuff mailing list]
  |}
  |}
|}
|}
† - service will be performed in a sister core facility (Harvard, DFCI, or Broad)<BR>
<BR>


[https://wikis.mit.edu/confluence/display/bmc ''BMC Internal wiki'']
[https://wikis.mit.edu/confluence/display/bmc ''BMC Internal wiki'']


<h2 align="center"> [http://whereis.mit.edu 68-322] ---- biomicro@mit.edu ---- 617-715-4533 </h2>
<h2 align="center"> CONTACT US </h2>
[http://whereis.mit.edu 68-322]<BR>
biomicro@mit.edu<BR>
617-715-4533

Latest revision as of 12:42, 25 August 2025

Welcome to the MIT BioMicro Center!

The MIT BioMicro Center is an integrated genomics core facility that provides both expertise and equipment for systems biology. The core has significant resources in sample preparation, next generation sequencing and in high throughput screening as well as bioinformatics and BioIT. The Center is a joint endeavor between the Department of Biology, the Koch Institute for Integrative Cancer Research (Integrated Genomics and Bioinformatics Core (IGB)), and the Department of Biological Engineering.

Assisted Services
Walkup Services
Sample Isolation
Library Preparation
Sample Quantification

Single Cell and Spatial

  • 10X CHROMIUM
    (5'RNA, 3'RNA, ATAC, multiome)
  • 10X VISIUM
    (Standard, High Density)
  • ELEMENT AVITI24 (in situ prep/sequencing)
Sequencing Technologies
Automation / Library Prep
Informatics Services
Data Analysis
BioIT/Research Computing
Education/Training/Seminars

† - service will be performed in a sister core facility (Harvard, DFCI, or Broad)


BMC Internal wiki

CONTACT US

68-322
biomicro@mit.edu
617-715-4533

Retrieved from "http://bmcwiki.mit.edu/index.php?title=BioMicroCenter&oldid=106864"