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The BioMicro Center is Hiring! (June 2025)[edit]

Core Manager (Program Scientist I, MIT-24971)[edit]

Position Overview:[edit]

Core Manager, BioMicro Center. The MIT BioMicro Center and the Koch Institute Genomics Core are seeking a core manager to join a highly collaborative team supporting a broad range of biological research projects in cancer, infectious disease, environmental health and other and topics in basic and applied biology. The core manager will focus on coordinating the day-to-day operations of the experimental laboratory, oversee the training of technical personnel and researchers on advanced techniques and methods, and be responsible for ensuring the quality and timeliness of the data being produced. The core manager will collaborate with the Director in evaluating and adopting new technologies and ensuring that the BioMicro Center/Genomics Core remain at the cutting edge of technology.

The MIT BioMicro Center / Koch Institute Genomics Core is a core facility that provides genomics and systems biology support and training for researchers in over 100 labs across multiple departments and centers. As such, the ability to understand a broad variety of biological questions and be familiar with adapting existing methodologies to new biological areas will be critical to the success.

Principal Duties and Responsibilities (Essential Functions):[edit]

The core manager will coordinate day-to-day operations for the shared resource in collaboration with Center Director. This includes coordinating projects and technical staff to ensure timely data production as well as ensuring robust data quality metrics. Success in management of the facility will require:

Maintaining up-to-date expertise in relevant instrumentation/research methods.
contributing original ideas to the research direction and/or methodologies used by scientists using the facility.
Devise and implement options for improving quality, identify potential problems and devises and implement solutions, which may include potential upgrades to equipment.
Responsible for the integrity, development and tracking of facility protocols, policies and procedures and performs
Contribute to the preparation of periodic progress reports or research narratives for grant proposals.
play a key role in determining the shared /core facility long-term strategy and financial planning/operations as an advisor to the BioMicro Center Director.
other duties assigned by the BioMicro Center Director.

Supervision Received[edit]

This position reports to the Director of the BioMicro Center and the Koch Institute Genomics Core. While this position consults with leadership and other members of the core on complex research matters, the position functions in a largely autonomous matter.

Supervision Exercised[edit]

This position is responsible for direct supervision of undergraduate researchers working within the shared resource including Northeastern Co-op students.

Qualifications and Skills[edit]

Minimum Education & Experience[edit]

PhD in the life sciences and a minimum of 2 years related experience in a research environment or Master's degree and minimum of 4 years related experience (which may include experience as a graduate student) with evidence of original or collaborative scholarship. Candidate must have direct experience with genomic technologies spanning multiple methodologies in a research setting.

Qualifications & Competencies:[edit]

Experience with identifying solutions using a systematic, multi-step approach. Maintain a broad knowledge of molecular biology and genomic methodologies and possess a solid understanding of modern sequencing techniques; able to rapidly grasp new fields of study. Experience working independently, the ability to multi-task, set priorities, produce polished results and thrive in a fast-paced environment. Demonstrated excellent communication skills, ability to work as part of a team and with users of diverse scientific/technical backgrounds. Ability to answer complex questions and demonstrate a deep understanding of systems biology. Knowledge and expertise in a UNIX/Linux environment.

@@ Line 1: / Line 1: @@
 {{BioMicroCenter}}
-= The BioMicro Center is Hiring! =
+= The BioMicro Center is Hiring! (June 2025) =
-== BioMicro Center: Informatics ==
+== Core Manager (Program Scientist I, MIT-24971) ==
-No full time or part time bioinformatics or bioIT positions are available at this time.
+=== Position Overview: ===
+<B> Core Manager, BioMicro Center.</B> The MIT BioMicro Center and the Koch Institute Genomics Core are seeking a core manager to join a highly collaborative team supporting a broad range of biological research projects in cancer, infectious disease, environmental health and other and topics in basic and applied biology. The core manager will focus on coordinating the day-to-day operations of the experimental laboratory, oversee the training of technical personnel and researchers on advanced techniques and methods, and be responsible for ensuring the quality and timeliness of the data being produced. The core manager will collaborate with the Director in evaluating and adopting new technologies and ensuring that the BioMicro Center/Genomics Core remain at the cutting edge of technology. <BR><BR>
-== [http://web.mit.edu/urop/ UROP 1] ==
+The MIT BioMicro Center / Koch Institute Genomics Core is a core facility that provides genomics and systems biology support and training for researchers in over 100 labs across multiple departments and centers. As such, the ability to understand a broad variety of biological questions and be familiar with adapting existing methodologies to new biological areas will be critical to the success.
-'''Project Title:''' Mutation Identification using Next-Generation Sequencing.<BR>
+=== Principal Duties and Responsibilities (Essential Functions): ===
-'''Project Description:''' The practice of genetics has changed dramatically over the last few years as a result of next generation sequencing. Rapid reductions in sequencing costs mean that it is now often less expensive and significantly faster to sequence an organism to find mutations, instead of using classical mapping methodologies.  Many challenges remain, however, and sorting through the large amount of sequence data to identify all of the alterations in an organism’s genome remains a complex problem. In addition, informatically sorting out which of those changes are associated with specific phenotypes and which changes are silent can be a tedious, and often inaccurate, process. You will be working with other bionformaticists to evaluate different algorithms for mutation identification and will be involved in creating automated processes to perform both basic and more advanced analyses of the data.<BR>
+The core manager will coordinate day-to-day operations for the shared resource in collaboration with Center Director. This includes coordinating projects and technical staff to ensure timely data production as well as ensuring robust data quality metrics. Success in management of the facility will require:
-'''Prerequisites:''' Programming with Python or Perl and 7.01 required. Interest in working multiple semesters in the lab is preferred.<BR>
+* Maintaining up-to-date expertise in relevant instrumentation/research methods.
-'''Contact:''' Please send a cover letter describing your research interests and a resume to [[BiomicroCenter:People|Stuart Levine]]
+* contributing original ideas to the research direction and/or methodologies used by scientists using the facility.
+* Devise and implement options for improving quality, identify potential problems and devises and implement solutions, which may include potential upgrades to equipment.
-== [http://web.mit.edu/urop/ UROP 2] ==
+* Responsible for the integrity, development and tracking of facility protocols, policies and procedures and performs
+* Contribute to the preparation of periodic progress reports or research narratives for grant proposals.
-'''Project Title:''' Analysis of the transcriptome using Next-Generation Sequencing.<BR>
+* play a key role in determining the shared /core facility long-term strategy and financial planning/operations as an advisor to the BioMicro Center Director.
-'''Project Description:''' Next generation sequencing has revolutionized molecular biology, allowing labs to sequence 100’s of millions of DNA fragments at a time, producing billions of basepairs of sequence every day. RNA sequencing protocols have adapted this technology to quantifying gene expression. The enormous quantity of data produced has made the informatics associated with these projects challenging and data processing is a limiting step in many studies. The particular complexities of RNA splicing have made this area one of the most challenging to produce meaningful data. You will be working with other bioinformaticists to evaluate different RNA-seq algorithms and will be involved in creating automated processes to perform both basic and more advanced analyses of the data.<BR>
+* other duties assigned by the BioMicro Center Director.
-'''Prerequisites:''' Programming with Python or Perl and 7.01 required. Interest in working multiple semesters in the lab is preferred.<BR>
+=== Supervision Received ===
-'''Contact:''' Please send a cover letter describing your research interests and a resume to [[BiomicroCenter:People|Stuart Levine]]
+This position reports to the Director of the BioMicro Center and the Koch Institute Genomics Core. While this position consults with leadership and other members of the core on complex research matters, the position functions in a largely autonomous matter.
+===Supervision Exercised ===
-== BioMicro Center: Genomics ==
+This position is responsible for direct supervision of undergraduate researchers working within the shared resource including Northeastern Co-op students.
-No full time or part time Technical Assistant positions are available at this time.
+===Qualifications and Skills===
+====Minimum Education & Experience====
-== COOPS ==
+PhD in the life sciences and a minimum of 2 years related experience in a research environment or Master's degree and minimum of 4 years related experience (which may include experience as a graduate student) with evidence of original or collaborative scholarship. Candidate must have direct experience with genomic technologies spanning multiple methodologies in a research setting.
-The BioMicro Center at MIT is a cutting edge genomics core facility which specializes in DNA sequencing and offers a wide range of services to researchers both inside and outside of MIT. The facility hosts and operates a large amount of advanced instrumentation as well as maintains significant integrated LIMS infrastructure to assist with data management and analysis. While maintaining a steady workflow, the BioMicro Center also performs experimental work aimed at optimizing and automating existing services offered at the facility. While co-ops are primarily responsible for quantification and sample prep, their tasks may extend further depending on the capabilities of the student. <BR>
+====Qualifications & Competencies:====
+Experience with identifying solutions using a systematic, multi-step approach. Maintain a broad knowledge of molecular biology and genomic methodologies and possess a solid understanding of modern sequencing techniques; able to rapidly grasp new fields of study. Experience working independently, the ability to multi-task, set priorities, produce polished results and thrive in a fast-paced environment. Demonstrated excellent communication skills, ability to work as part of a team and with users of diverse scientific/technical backgrounds. Ability to answer complex questions and demonstrate a deep understanding of systems biology. Knowledge and expertise in a UNIX/Linux environment.
-Responsibilities and Duties:
-* Quantification of RNA and DNA samples
-* Creating Illumina-ready libraries for sequencing using a number of techniques
-* Optimizing protocols whenever necessary
-* Maintaining a detailed lab notebook
-* Inputting samples into central database
-* Interacting with users and researchers from inside and outside of the MIT community
-Job Skills Required:
-* Proficiency in basic lab skills (e.g. pipetting, proper sterile technique, dilutions)
-* Prior lab experience in a molecular biology setting
-* Maintenance of organized lab notes for a large number of projects
-* Solid mathematical background.
-* Moderate computer skills (e.g. Microsoft Office, Google Calendar)
-* Acuity in maintaining sufficient lab supplies
-* Proficient interpersonal skills
-* Ability to work effectively in a group environment and independently
-* Ability to learn scientific principles and concepts efficiently
-* Motivational attitude, flexibility, and versatility when working in a rapidly growing environment.