Editing BioMicroCenter:News (section)

== BioMicro Center News ==




=== SPRING 2025 ===

<B>Spatial Transcriptomics:</B>
- The BioMicro Center has recently expanded our spatial 'omics options with the addition of the AVITI24. This upgrade to our existing Element sequencer enables it to do in situ sequencing. For this method, cells are either grown directly onto a flowcell or placed there, fixed and panels of transcripts identified. The system can currently handle up to 350 transcripts and dozens of antibodies with cellular features identified as well (nuclei, cytoskeletin, membrane, etc.). More information is on the Element website. The upgrade was a generous gift from Scott Ritterbush.

TO highlight the new capabilities, we have a special seminar upcoming. Molly He, CEO of Element, will be speaking at the KI on May8 (12n). She'll be talking both about the science of the AVITI and the AVITI24, but also about building a company that is competing with the near monopolistic power of Illumina. I hope you can make it to what should be a fantastic seminar.

<B>High Output Sequencing:</B>
- The BioMicro Center is now supporting sequencing on Illumina's NovaSeqX through collaborations with our sister shared resources in the Boston area.  Practically, this will still act like any other sequencing: You will still submit on ilabs and bring the samples to the core. We will preform all the QC and receive the data back, process it, confrim the quality of the data (resolving any technical issues) and place it in your data delivery folders. Since the rates we can share with you are below the published rates, we cannot put these rates on our website, but they are visible in ilabs.

<B>Website:</B>
- Lastly, the website we have used for well over a decade appears to have failed. Openwetware, a scientific wiki platform, was built at MIT many years ago, starting in Bldg68, and the wiki seemed like a natural fit for the core and worked well for many year. The website failed on us a few weeks ago. We have set up a new page (still reachable at biomicro.mit.edu) but our backup was a few months old. We're working to get it back up to date and apologize for any missing information. If you do have questions or see broken links, please do let us know at biomico@mit.edu
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